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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWSG1
All Species:
15.15
Human Site:
Y159
Identified Species:
37.04
UniProt:
Q9GZX9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZX9
NP_065699.1
223
25017
Y159
S
N
N
V
H
A
P
Y
S
S
D
K
E
H
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099214
223
24940
Y159
S
N
N
V
H
A
P
Y
S
S
D
K
E
H
M
Dog
Lupus familis
XP_547668
223
24908
Y159
S
N
N
V
H
A
P
Y
S
S
D
K
E
H
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP52
222
24782
F158
S
N
N
V
H
A
P
F
P
S
D
K
E
R
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515912
148
16781
K88
H
A
P
Y
S
S
D
K
E
H
M
C
T
V
V
Chicken
Gallus gallus
Q98T89
224
24885
Y160
S
N
N
I
H
A
P
Y
S
S
D
K
E
H
M
Frog
Xenopus laevis
Q9I8M9
218
24385
H154
N
V
S
V
Q
V
S
H
S
N
E
K
E
H
M
Zebra Danio
Brachydanio rerio
Q9DGH0
217
23906
S153
Q
N
I
S
L
P
T
S
S
A
Q
D
D
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54356
249
27202
A144
N
G
N
G
N
G
N
A
G
S
A
G
V
T
L
Honey Bee
Apis mellifera
XP_392649
243
27526
K152
N
E
E
V
H
P
L
K
P
N
V
M
T
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
95.5
N.A.
93.2
N.A.
N.A.
65.9
90.1
81.6
69
N.A.
32.5
35.7
N.A.
N.A.
Protein Similarity:
100
N.A.
99.5
97.7
N.A.
94.1
N.A.
N.A.
65.9
93.3
87.8
81.6
N.A.
50.2
53
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
80
N.A.
N.A.
0
93.3
40
13.3
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
13.3
100
73.3
33.3
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
50
0
10
0
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
50
10
10
0
0
% D
% Glu:
0
10
10
0
0
0
0
0
10
0
10
0
60
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
10
0
0
10
0
0
10
0
0
0
% G
% His:
10
0
0
0
60
0
0
10
0
10
0
0
0
50
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
20
0
0
0
60
0
0
0
% K
% Leu:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
60
% M
% Asn:
30
60
60
0
10
0
10
0
0
20
0
0
0
0
10
% N
% Pro:
0
0
10
0
0
20
50
0
20
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
50
0
10
10
10
10
10
10
60
60
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
20
10
0
% T
% Val:
0
10
0
60
0
10
0
0
0
0
10
0
10
20
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _